Topic                                                                       Chapters
I.     Transmission Genetics                                      

        Introduction and Overview                                     1,2

        Mendelian Genetics                                                   2

        Modified Ratios and Non-Mendelian Inheritance   3

        Probability and Statistics                                           2

        Mitosis and Meiosis                                                  4

        Sex Determination and Chromosomal Variation     4

        Linkage and Crossing Over                                      5

        Genetic Mapping Using Linkage Data                    5

        Exam 1

II. Molecular Genetics

        DNA Structure and Organization                        6,9(220-4)

        DNA Replication and Recombination                   7

        Gene Structure, Transcription                            8,9
           & RNA Processing

        Translation and Proteins                                      10

        Gene Regulation                                                 8,9

        Gene Regulation                                                 8,9

        Exam 2

III. Changes in the Genome

        Recombination and Transformation                  13

        DNA Cloning and Recombinant Technology    15

        Gene Mapping and DNA Analysis                    16

        Mutation and Repair                                          11

        Transposable Elements                                      12

        Exam 3

IV. Disciplines and Topics

        Developmental Genetics                                   14

        Genetics of Cancer                                            17

        Population Genetics                                           19

        Imprinting                                               pp.410-12

        Extranuclear Inheritance 18

        Review

        Final Exam 12:15-2:15

Week   Date      Laboratory Topic                                                    Lab Manual Pages

1           Jan 23   Drosophila Experiments in Genetics                     1-10

2           Jan 30   Drosophila and Maize Experiments                      11-18
                           in Genetics: Dihybrid Crosses

3           Feb 6     Principles of Probability/ The Chi-Square Test    19-26, 27-39

4           Feb 13   Cell Reproduction: Mitosis and Meiosis             41-49, 50-58
                            Polytene Chromosomes from Drosophila           75-78

5           Feb 20   Sex Chromosomes and Gene Transmission        79-87
                           Sex Check                                                              89-93

6           Feb 27   Genetics of Ascospore Color in Sordaria            139-146
                           Chromatography of Drosophila Mutants            201-206

7           Mar 6    Human Chromosomes                                          95-119

8           Mar 20  DNA Isolation                                                      Handout (153)

9           Mar 27  Restriction Endonuclease Digestion and
                            Gel Electrophoresis of DNA                              Handout (159)

10         Apr 3     RFLPs and Pedigree Analysis                            Handout

11         Apr 17   PCR                                                                      Handout

 
12         Apr 24   Polygenic Inheritance: Fingerprint Ridge Count     221-230

13         May 1   Population Genetics: The Hardy-Weinberg Law     231-241

14         May 5   Applied Human Genetics                                          251-266

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