This course provides survey of the leading non-infectious and non-cancerous diseases in the industrialized world. This course will explore the molecular mechanisms of disease, clinical symptomology, and pharmacological treatment. Students will be expected to conduct thorough research on a given disease and present their results in a poster session.
Prerequisites: BIO 306, 313 and CHM 300 or 304. Lect. 3. Offered Sem. II.
 

Instructors:   Aaron Monte, Room 4020 Cowley Hall, 785-8263, monte@mail.uwlax.edu
                      Scott Cooper, Room 3022 Cowley Hall, 785-6983, cooper@mail.uwlax.edu
                      Guest lecturers from Gundersen Lutheran Medical Center and UWL will present some of the clinical lectures.
 

Lectures:       MWF from 8:50-9:45 in room 301 Cowley Hall.  You are responsible for all material covered in class,
                       homework assigned, and any changes announced in exam dates.
 

Textbook:      The text is meant to serve as a resource, some lectures may not follow the textbook very closely.

                       Essential Pathology. Second Edition. By Rubin and Farber
 

Exams:          (300 points)   There will be three scheduled exams [100 points each].
 
Poster Presentation:  (100 points)  Each student will present a poster on an assigned disease.  If you have a specific
                        disease that you would like to research, and that we don’t cover in depth in lecture see me for permission.
                        The posters will be divided into four groups and each group will be presented on a different day.
                        The material on the posters will be fair game on the final exam.  Posters will be graded by the instructor
                        and by four students.  Abstracts for the posters will be due two weeks before the first poster session
                        and will be distributed to each student.

Final Exam:   (200 points) There will be a comprehensive final exam covering all lectures and assigned readings.
 

                        This course will count as an elective for students in the Cellular and Molecular Biology Concentration
                        and the Biomedical Science Concentration.
 

Syllabus

Week                 Topic                                                                     Guest Speaker

 1                         Cell injury
                                A. Inflammation
                                B. Repair and regeneration
                                C. Immune response

2                         Intro to Pharmacology
                                A. Overview of drug action
                                B. Molecular targets
                                C. Pharmacodynamics
                                D. Pharmacokinetics

3                         Autoimmune diseases and anemias                         Wayne Bottner
                                A. Rheumatoid arthritis
                                B.  Lupus
                                C.  Anemias
 
                            EXAM 1

4                         Hemodynamic disorders                                         John Farnen
                                A. Hemostasis and Thrombosis
                                B. Clotting and bleeding disorders
                                C. Stroke

5                         Heart Disease                                                         Ward Brown
                                A. Atherosclerosis
                                B. Familial Hypercholesterolemia
                                C. Myocardial Infarction

6                         Respiratory Disease                                                 Todd Mahr
                                A. Emphysema
                                B. Bronchitis
                                C. Asthma
                                D. Cystic Fibrosis

7                         Metabolic Disease                                                 Peggy Maher
                                A. Diabetes
                                B. Obesity

                            EXAM 2

8                         Neurouscular Diseases
                                A. Muscular dystrophy
                                B. Epilepsy
                                C. Multiple Sclerosis

9                         Neuromuscular Diseases
                                A.  Alzheimer Disease
                                B.  Huntington Disease
                                C.  Parkinson Disease

10                        Psychiatric Illnesses
                                A.  Depression
                                B.  Schizophrenia
                                C.  Anxiety

11                         EXAM 3
                             Poster Sessions

12                         Poster Sessions

13                         Genetic Testing and Drug Development

14                         Developmental and genetic diseases                     Marc Williams
                                A. Metabolic diseases
                                B. Developmental diseases
                                C. Genetic counseling                                       Kevin Josephson

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If you have any questions about or additions to these pages please contact Tom Volk, volk_tj@mail.uwlax.edu