Sandra K. Koster, Ph.D. Lecturer
Department of Chemistry
4003 Cowley Hall
SYLLABUS AND LAB SCHEDULE
| ANNOUNCEMENTS | SYLLABUS | SCHEDULE | ASSIGNMENTS | Handouts |
| Sandra Koster's Home Page | Department of Chemistry | UWL Home Page |
CHM 300L53 - Survey of Organic Chemistry Laboratory Course Outline - Fall 2008
Instructor: Dr. Sandra Koster / 4003 CH / phone: 785-8282 Class Meets: Tuesday and Thursday 7:45-9:45 AM in room 412 CH
Text: Pavia, D.L.; Lampman, G.M.; Kriz, G.S.; Engel, R.G. Introduction to Organic Laboratory Techniques: A Microscale Approach 3rd Edition Saunders College Publishing: New York, NY, l999.
Objectives: To provide an understanding of the practical aspects
of
organic chemistry. Theories discussed in lecture will be explored in
laboratory
to illustrate how organic reactions, separations, and analyses are
carried
out in "the real world." Emphasis is placed on keeping a reliable
laboratory
notebook, and in gaining experience with common lab techniques,
instrumentation,
and organic chemicals and reagents.
| Experiment | Skill/Technique Topic | Reading/Technique | ||
| Check-In, Laboratory Safety | Intro to Microscale Laboratory | pp 2 – 49 | ||
| Synthesis of Aspirin (Acetylsalicylic Acid) (exp 8) |
Basic Equipment and Techniques Reaction Methods Filtration Physical Constants: Melting Point |
pp 100 – 109
tech 1 and 2 |
||
| TLC Analysis of Analgesics | See also essay from
Experiment 10, pp 114, 115 Thin-Layer Chromatography (TLC) |
Handout tech 14 |
||
| Molecular Models and Alkanes | Basic Use of Molecular Model | Handout | ||
| Isolation of Caffeine from Tea Leaves |
|
|
||
| Isolation of Chlorophyll and Carotenoid Pigments From Spinach | See also essay from
Exp 15, pp 154 - 159 Solvent evaporation Extractions, Drying Agents Column Chromatography Thin-Layer Chromatography (TLC) |
Handout tech 3.9 tech 7.1-7.7, 7.9-7.11 tech 12 tech 14 |
||
| Nitration of Methyl Benzoate |
Filtration Crystallization (Craig tube method) Melting point Infrared (IR) Spectroscopy |
pp 342 - 345 but procedure is from handout tech 4.1-4.6 tech 5 (5.4 in particular) tech 6.1-6.8 tech 19 (19.6 in particular), Appendix 3 |
||
| Simple and Fractional
distillation Study of a Methanol,
n-propanol mixture |
Simple Distillation Fractional Distillation Gas Chromatography Refractometry |
Handout tech 8.1-8.3 tech 10 tech 15 (also handout) tech 18 |
||
| Isolation of Limonene from Citrus Peels (Handout) |
See also essay from
Exp 13, pp 135-139 Extractions, Drying Agents Distillation Setup Steam Distillation Infrared (IR) Spectroscopy Boiling point – Microscale method Refractometry Polarimetry |
Handout tech 7.1-7.7, 7.9-7.11 page 629 tech 11 tech 19.1,19.2; Appendix 3 tech 6.9, 6.10 tech 18 tech 17 |
||
| Midterm Exam (10-28) |
||||
| Reduction of Benzil to Hydrobenzoin |
See also essay on
sodium borohydride reductions from Experiment 33 pp 267-269 Melting point Infrared (IR) Spectroscopy 1H-Nuclear Magnetic Resonance |
Handout tech 6.1-6.8 tech 19 (19.6-Dry Film Technique) Appendix 3 Appendix 4 |
||
| Synthesis of Triphenylmethanol (exp 31A) | Crystallization (Semimicroscale)
Melting point Infrared (IR) Spectroscopy |
pp 292 - 299 as modified by handout tech 3 tech 6.1, 6.8 tech 5.3 tech 19 (19.6-Dry Film Technique) |
||
| Synthesis of Banana Oil or other Flavoring Ester | Reaction Methods Simple Distillation Boiling point – Microscale method Refractometry (optional) Infrared (IR) Spectroscopy Review NMR Spectroscopy |
pp 128 – 133 as modified by handout tech 3.2-3.4 tech 8.1-8.3 tech 6.9, 6.10 tech 18 tech 19.1, 19.2; Appendix 3 Appendix 4 |
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| No Lab Thanksgiving week (11-25) |
||||
| Casein and Lactose from Milk |
Handout | |||
| Check Out, Final Exam (12-9) |
CHEM 300 LABORATORY COURSE ADMINISTRATION
Each student must purchase a lab research notebook (automatic carbon,
double
page numbered and bound) from the University Bookstore. The carbon copy
of
each completed experiment will be turned in as part of the laboratory
report
along with selected questions concerning the completed experiment. See
the
separate handout on the laboratory notebook for details on how your
reports
are to be structured.
A pair of approved safety goggles is required before any laboratory work can be done. Safety goggles are available from the Chemistry Stockroom or the University Bookstore. Read the safety regulations carefully and be sure you locate all safety equipment in the lab: fire extinguishers, eye wash and safety shower. The tear-off sheet regarding the regulations should be turned in just prior to the start of your first experiment. There will be additional safety information given during the laboratory periods and in your text. Repeated failure to follow safety regulations will result in dismissal from the laboratory for the day or the course as decided by the instructor.
All reading assignments are to be completed prior to the beginning of each new lab experiment and prior to the lecture introduction to the experiment. This lecture will be given at the start of each laboratory period.
GRADING subject to minor changes:
a. Lab reports ~11 reports x 15 pts/report ~ 165 pts.
b. Molecular Models Problem Set 10 pts.
c. Distillation Study Report 20 pts
c. Ester NMR Problem Set 5 pts.
b. Midterm exam 50 pts.
c. Final exam 60 pts.
d. Safety, notebook checks, attendance, product evaluations, up to ± 10 pts.
~300 pts. TOTAL
Lab report grading: the grade will be based on the completeness, legibility and writing style of the lab write-up, the assigned questions and the experimental results. A letter grade for the laboratory portion of the course will be turned in to your lecture instructor based on the following approximate scale (with +’s and - ’s added as appropriate):
> 90% A
80 – 89% B
70 – 79% C
60 – 69% D
Email me at koster.sand@uwlax.edu
Last Modified 10/10/08