500 Cr. 2
Orientation in Clinical Microbiology
This course will explore career
opportunities within clinical microbiology including public health, diagnostic
testing, basic and industrial research and development, and pharmaceutical
sales. Discussion will focus on academic and professional requirements for each
career track. The course will also cover clinical laboratory management,
infection control, diagnostic techniques, and communication skills. Offered by
resident faculty and visiting lecturers. Prerequisite: MIC 230 or equivalent;
admission to the clinical microbiology program. Offered Sem. I.
An introduction to how the immune system
protects against infectious disease and how it can contribute to disease. A
discussion of fundamental characteristics of innate and acquired immunity is
followed by study of antigens, antibodies, the major histocompatibility complex,
T and Blymphocyte recognition of antigen and response, cytokines and immune
regulation, hypersensitivity reactions including allergies, and the immune
system in AIDS. Lect. 2, Lab. 4. Prerequisite:
MIC 230; BIO 303 or 313 and CHM 300 or 303 recommended.
The study of pathogenic bacteria and
their relationships to disease; principles of infection and pathogenesis, and
unique properties of pathogens. Laboratory emphasis is on techniques for
isolation and identification of pathogenic bacteria. Not applicable to biology
major; may be applied to the microbiology, clinical laboratory science major
and/or degree as well as an elective for the biology biomedical concentration.
Lect. 2, Lab 4. Prerequisite: MIC 230; MIC 406/506 or concurrent enrollment.
An in-depth study of the bacterial and
bacteriophage genome with emphasis on the central dogma. Specific topics include
DNA replication, transcription and translation, DNA mutation and repair,
regulation of gene expression, mechanisms of genetic exchange, plasmid structure
and function, transposition, gene mapping and recombinant DNA technology.
Laboratory emphasis is on the techniques used in bacterial mutagenesis, genetic
exchange, gene mapping, and gene cloning. Lect. 2, Lab. 6. Prerequisite: MIC
406, three semesters of college chemistry including organic, and admitted to
microbiology major. Offered Sem. I.
An introduction to viruses and their
interactions with host organisms. Special emphasis is placed on the structure
and replication cycles of virus families with medical importance. Prerequisite:
MIC 230 and MIC 426 or BIO 306 or BIO 435/535 and three semesters of college
chemistry to include organic chemistry. Offered Sem. II.
A laboratory course designed to
introduce fundamental techniques used to study viruses in medicine,
biotechnology and research. Emphasis is on procedures used to safely handle
viruses, grow them in tissue culture, and the molecular biological, biochemical
and immunological techniques used to detect and analyze viruses.
Lab. 4. Prerequisite: MIC 230 and MIC 416 or BIO 306 or BIO 435/535 and
three semesters of college chemistry to include organic chemistry. Offered Sem.
An in-depth study of bacterial structure
and function, catabolic and anabolic pathways, regulation, and macromolecular
synthesis. Laboratory emphasis is on current techniques used to examine
bacterial structure and metabolism such as macromolecular separations and
quantification, use of radioisotopic tracers and quantification of enzyme
activity. Lect. 2, Lab. 6. Prerequisite: MIC
406, MTH 150 or higher, CHM 300 (or 303). Admitted to microbiology major.
Offered Sem. II.
A study of environmental factors
affecting the growth, activity, and destruction of micro-organisms in food;
principles of food spoilage; preservation of foods, including basic methods and
their application to foods; food-borne intoxications and infections; indicator
organisms; sanitation and microbiological standards in foods. Laboratory
instruction includes quality control methods, sampling methods, and techniques
to identify important microorganisms in foods, and data interpretation and
analysis. Lect. 2, Lab. 4. Prerequisite: MIC 230; BIO 412/512 strongly
recommended. Offered Sem. II.
Industrial and Fermentation Microbiology
A study of microbiology and biochemistry
of food fermentations; bioconversions; production of antibiotics, vitamins,
amino acids and organic acids. Starter culture systems will be examined.
Prerequisite: MIC 230; MIC 426/526 strongly recommended. Offered Sem. I.
Fermentation Microbiology Laboratory
Principles of fermentation science and
biotechnology with emphasis on industrial and food fermentation processes.
Laboratory emphasis is on the use of various fermentation systems that generate
useful products including fermented food and beverages, pharmaceuticals, fine
chemicals and other gene products. Lab. 4. Prerequisite: MIC 426 or 427 and
three semesters of college chemistry. Offered Summer Session.
Aquatic Microbial Ecology
An ecological study of bacteria,
cyanobacteria and algae of aquatic ecosystems. Topics include microbial
strategies for survival under various environmental conditions, the role of
microorganisms in biogeochemical cycling of elements, interactions of
microorganisms with other aquatic biota, the role of microorganisms in pollution
problems, and applications of microbial ecology to biotechnology. Laboratory
emphasis is on experimental design and sampling techniques, quantification of
microbial biomass, and measurement of microbial activities in aquatic habitats.
One weekend field trip required. Lect. 2, Lab. 3. Prerequisite: MIC 230 and
three semesters of college chemistry; BIO 341 strongly recommended. Offered Sem.
I, alternate years.
In this course, students will use computers to study and compare the sequence of nucleotides in DNA or RNA, or the amino acids in a protein. Computers also are used to examine the three dimensional structure of proteins. Being able to manipulate and study this information is the basis for the current revolution in biotechnology. Topics include evolution, taxonomy, genomics and understanding disease. This course provides students an opportunity to explore the relationships between biology, microbiology, chemistry and computer science. Lect. 1, Lab. 2. Prerequisite: BIO 306 or MIC 230 (BIO 435 or MIC 416 recommended). Cross-listed with BIO 440/540; may only earn credit in MIC or BIO. Offered Sem. II and J Term.
Plant Microbe Interactions
This course will explore in-depth
various ways that plants interact with microbes in the environment, at the
macroscopic, cellular, and molecular levels. Case studies will include both
parasitic and mutualistic (symbiotic) interactions. Microbes include fungi,
bacteria, nematodes, and viruses. Includes plant pathology and studies of the
beneficial relationships between plants and microbes. Inquiry based labs are
integrated into the lecture and discussion sessions. Lect. 2, Lab. 2.
Prerequisite: BIO 204, MIC 230, EITHER BIO 306 or MIC 416. Offered Sem. II, even
Mechanisms of Microbial Pathogenicity
The study of mechanisms of microbial
pathogenicity including both overt microbial factors and complex interactions
with the host that produce symptoms of disease. The cellular, biochemical,
molecular, and genetic bases for modern understanding of microbial disease will
be included. Prerequisite: MIC 406/506 or equivalent and MIC 407/507 or
equivalent. Offered Sem. II. (alternate years)
Field and Laboratory Methods in Vector-borne and Zoonotic Disease Research
This course will explore methods used in
vector-borne and zoonotic disease research. Students will learn current field
and laboratory techniques used to understand the epidemiology, spread, and
transmission of vector-borne, infectious diseases (VBID?s) and other zoonotic
diseases. Emphasis will be placed on sample collection in the field from birds,
mammals, and vectors as well as processing and testing samples from the
causative agents of West Nile encephalitis. Eastern equine encephalitis, Lyme
disease, Human granulocytic ehrlichiosis (HGE), and others. Attention will focus
on experimental design and computer methods used in study design and
application. Lect.10, Lab 30. Prerequisite: MIC 230 or equivalent. Course
offered off campus. Offered Summer Session.
Symposium in Microbiology
Varying topics in microbiology with a
specific title assigned to each. Offered by resident faculty or visiting
lecturers. Prerequisite: MIC 230. Repeatable for credit?maximum 6.
714 Cr. 3
The application of molecular-genetic
analysis to problems in modern biology. The course will cover the fundamentals
of genetic analysis in both prokaryotic and eucaryotic systems. Assigned
readings from current literature will be discussed and evaluated. A variety of
topic areas will be considered, including ecology, biotechnology,
bioremediation, food science, medicine, and basic research. Prerequisite: a
previous course in genetics, microbial genetics or molecular biology.
(Cross-listed with BIO.) Offered Sem. II, alternate years.
721 Cr. 1-2
Directed readings or presentation of
material not available in formal departmental courses. (Cross-listed with BIO.)
Repeatable for credit ? maximum 4 between BIO and MIC.
730 Cr. 2
Biodegradation and Bioremediation of Environmental Contaminants
Microbes are able to breakdown, or
biodegrade, a wide variety of compounds including some considered hazardous to
human health and/or the environment. The use of microbes as biological agents to
reclaim polluted soils and waters is called bioremediation. This course will
explore some of the better-studied mechanisms used by microbes to degrade and
detoxify contaminants. Practical aspects for the use of microbes in
bioremediation and some specific examples will also be covered. In addition, the
students will present and discuss a series of special topics such as nuclear
waste bioremediation or current clean-up efforts in the news. Prerequisite: one
semester organic chemistry, MIC 230 or equivalent microbiology course. Offered
Sem. I, alternate years.
751 Cr. 1
In this course students will research
and present a formal seminar on a selected topic in biology or microbiology.
Students are also expected to actively participate in discussion of other
seminar presentations. (Cross-listed with BIO.) Repeatable for credit ?
753 Cr. 2
Epidemiology of Infectious Disease
This course examines the causes,
distribution, control, and prevention of infectious disease in human
populations. Basic epidemiological concepts, including study design, analysis
and modeling of infectious disease data, establishing causal relationships,
detecting confounding factors, and assessing risk will be presented. Emphasis
will be placed on issues of special interest to the clinical epidemiologist
including laboratory diagnosis used in outbreak investigations by
microbiological, serological and molecular techniques. In addition, methods to
evaluate the accuracy and usefulness of diagnostic tests will be examined.
Prerequisite: MIC 407/507 or equivalent course. MTH 145 or MTH 250 or HED 755.
Offered Sem. II.
755 Cr. 2
An in-depth study of advanced topics in
immunology, primarily focusing on the genetics, mechanisms, and regulation of
the immune system. Aspects of the immune response in a variety of disease
conditions (infectious and non-infectious) will be discussed. Prerequisite: MIC
406/506 or equivalent. Offered Sem. I. (alternate years)
761 Cr. 2
Research and Seminar in Microbiology
In-depth literature review of a current
research topic in microbiology. As part of the requirements for this course and
for the degree each student must complete an acceptable seminar paper under the
direction of an assigned faculty member. Not applicable to students pursuing a
Plan A thesis.
770 Cr. 5
Clinical Microbiology Practicum I
Students spend 9 full-time weeks (30
hrs/wk) in the clinical laboratories at Gundersen Lutheran Medical Center where
they receive training and hands-on experience in clinical microbiology,
immunology, parasitology, mycology, and virology. In addition, students will actively participate with
physicians, residents, and medical students in weekly infectious disease rounds
and journal club. Prerequisite: acceptance into clinical microbiology program.
780 Cr. 4
Clinical Microbiology Practicum II
Students spend 6 full-time weeks (30
hrs/wk) in the clinical laboratories at Marshfield Laboratories/St. Joseph?s
Hospital/Marshfield Clinic. Training will include hands-on experience with
state-of-the art molecular biology techniques. Specific exercises involving
molecular epidemiology and infection control will be emphasized. Students will
also participate in infectious disease rounds and journal club. Prerequisite:
acceptance into clinical microbiology program.
790 Cr. 2
Clinical Microbiology Practicum III
Students will spend 2 full-time weeks
(30 hrs/wk) at the Wisconsin State Laboratory of Hygiene for public health
training in mycobacteriology, sexually transmitted diseases, food-and
water-borne diseases, and community respiratory illness surveillance. Emphasis
will be on prevention and control programs and outbreak responses currently in
place at the Wisconsin Department of Health. Prerequisite: MIC 770 and MIC 780.
799 Cr. 1-15
Research: Master?s Thesis
Independent research in microbiology on a problem selected for a thesis under the direction of an assigned faculty major adviser. For students following Plan A. Repeatable for credit ? maximum 15; maximum six applicable to degree.
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Modified:June 13, 2012