MICROBIOLOGY (MIC)

 

 

College of Science and Allied Health

Department Chair: Michael Winfrey

3028 Cowley Hall, 608-785-6964

e-mail: winfrey.mich@uwlax.edu

 

Professor: Winfrey; Associate Professors: Rajagopal, Rott; Assistant Professors: Bratina, Schwan, Taylor; Lecturers: Anglehart, Voyles.

 

 

Center of Excellence in Microbiology

The University of Wisconsin System and the Board of Regents have identified the Microbiology Program and UW-L as a Center of Excellence based on the exceptional quality of the undergraduate laboratory science education. The Microbiology Program has been nationally recognized for the overall quality of the program and prepares its graduates for a diversity of professional opportunities at the baccalaureate level. Since the inception of a major in 1984, more than 95 percent of the microbiology graduates interested in employment have obtained positions in hospitals, clinics, private laboratories, food and fermentation industries, pharmaceutical industries, universities, and government agencies.

 

Microbiology is also an excellent curricular track to prepare students for graduate or professional schools (medical, dental, veterinary, optometry). Microbiology provides exceptional training in a fundamental discipline in their post-graduate education, and also provides abundant employment opportunities for students who do not go on to graduate or professional school.

 

The Microbiology major is housed within the Department of Microbiology and provides students with an extensive curriculum with a strong laboratory emphasis. Microbiology faculty have obtained over one million dollars in grant funding within the past decade to ensure that students gain experience in the latest state-of-the-art techniques. Students may choose from an extensive list of microbiology electives and emphasize one of five curricular tracks: (1) medical microbiology, (2) research and developmental microbiology, (3) biotechnology and microbial genetics,   (4) food and fermentation microbiology, or (5) environmental microbiology. All microbiology majors receive individual counseling throughout their undergraduate years and they may tailor their curriculum to meet their  individual career goals. An active American Society for Microbiology recognized Microbiology Club enhances the educational experience. For additional information regarding the Microbiology Center of Excellence, contact the Microbiology Department Chair, Cowley Hall, University of Wisconsin-La Crosse, La Crosse, WI 54601.

 

 

 

Microbiology Honors Program

See department chair for requirements.

 

 

Microbiology Major

(All colleges, excluding Teacher Certification programs) — 40 Microbiology/Biology credits:

A.            Biology Core: BIO 105 and a second biology course (BIO 204, 210, 303, or                              312/313*)

B.            Microbiology Core: MIC 230, 406, 407, 416, 425, 461

C.            Microbiology/Biology electives (nine credits; at least six credits from List I, a                        maximum of two credits from List III. One course from List II strongly

                recommended):

                List I:      MIC 350, 420, 421, 426, 427, 428, 434, 454, 460

                List II:     BIO 406, 412, 413, 449, 463; MLS 425

                List III: MIC 489, 499

D.            Additional Requirements: One course in physics (PHY 125 or 103 and 104 or 203   and 204) and a minimum of 24 credits of chemistry are required including: CHM

                103, 104, 300 (or 303, 304, and 305), 301, 325 (or 417 and 418)      

 

 

Microbiology Major

Pre-Professional Concentration (All colleges, excluding Teacher Certification programs) — 40 Microbiology/Biology credits:

A.            Biology Core: BIO 105, 306, 312, 313

B.            Microbiology Core: MIC 230, 406, 407, 416 or 425, 461

C.            Microbiology/Biology electives (six                 additional credits; at least three credits                           from List I, a maximum of two credits from List III):

                List I:      MIC 350, 420, 421, 416, 425, 426, 454

                List II:     BIO 406, 412, 413, 435, 463

                List III: MIC 489, 499

D.            Additional Requirements: One course in math (MTH 151, 205 or 250, 175 or                            207), eight credits of physics (PHY 103 and 104 or 203 and 204), and a                                      minimum of 27 credits of chemistry   including: CHM 103, 104, 301, 303,                    304, 305, 325 (or 417 and 418).

 

Students must maintain a cumulative GPA of 3.00 to stay in the Pre-professional Concentration within the Microbiology major. Students who fall below a GPA of 3.00 will be given one additional semester to raise their GPA to 3.00. Pre-professional Concentration Microbiology majors that do not maintain a GPA of 3.00 may transfer to the general Microbiology major.

 

 

Microbiology Major

Environmental Science Concentration (All colleges, excluding Teacher Certification programs) — 40 Microbiology/Biology credits:

A.            Biology Core: BIO 105 and a second biology course (BIO 204, 210, or 303)

B.            Microbiology Core: MIC 230, 350, 416, 425, 434, 461

C.            Microbiology/Biology electives (11 credits; at least five credits from List I,                             at least three credits from List II, and a maximum of two credits from List III):

                List I:      MIC 406, 407, 420, 421, 427, 428, BIO 307 or 341 or 464*,                                              447, 448, 449

                List II:     BIO 406, 412, 463

                List III:  MIC 489, 499

 

D.            Additional Requirements: MTH 205 or 250 and 175 or 207; one course in                                 physics (PHY 125 or 103 and 104 or 203 and 204), and a minimum of 24                    credits of chemistry are required, including: CHM 103, 104, 300 (or 303,                    304, and 305), 301, 325 (or 417 and 418).

 

In order for any Microbiology majors (including concentrations) to continue in upper division microbiology course work they must:

 

1.             Complete BIO 105, a second BIO course (204, 210, 303, or 312) and MIC 230.

2.             Complete three semesters of chemistry (CHM 103, 104 and 300 or 301 or 303).

3.             Have a minimum GPA of 2.5 in the six science courses listed above.

4.             Complete one semester of math (MTH 150 or higher) with a grade of C or better.

 

Microbiology students may then apply for continuance in the microbiology program (usually after the completion of three or four semesters). Application materials may be obtained from the microbiology adviser. Admission is competitive and not all students meeting the minimum requirements are guaranteed admission. Students not meeting the minimum requirements may petition for admission into the program, and may be accepted depending on space availability. The number allowed in the microbiology program is flexible and is dependent on room in upper-division microbiology courses.

 

 

+ above a course number indicates a General Education course.

 

+

MIC        100                                                                                                                                     Cr. 4

Microbiology and Human Affairs

Microbiology plays an integral role in human affairs and our daily lives. Some microorganisms have caused tremendous suffering throughout history, however many microbes have also provided countless benefits to humans and play vital roles in essential global cycles. This course examines the science of microbiology and the impact of microbiology on human affairs. The principles of microbial diversity, cell structure, growth and reproduction, global processes, disease, and prevention of disease are covered. Each topic provides a basis for discussion of current issues where microorganisms play a role. The laboratory provides an inquiry based approach to examining the diversity of microorganisms and their role in disease, spoilage, genetic engineering, food and antibiotic production, agriculture, and the environment. Not applicable to a major in microbiology or biology. Lect. 3, Lab. 2.

 

MIC        102                                                                                                                                     Cr. 1

Global Bioterrorism

An overview of current potential biological warfare agents. Topic areas will include an historical overview, an explanation of differences in the classes of biological warfare agents, our preparedness to meet this threat, and counter measures to prevent a biological warfare catastrophe. Offered Sem. I.

 

MIC        230                                                                                                                                     Cr. 4

Fundamentals of Microbiology

An introduction to the fundamental principles and  applications of microbiology with an emphasis on the role of microorganisms, especially bacteria, in human affairs. Lecture topics include microbial diversity, cell structure and function, growth and metabolism, genetics, genetic engineering, control of microbial growth, host-parasite interactions, immunology, microbial ecology and applied microbiology. Laboratory emphasis is on methods used to cultivate and identify bacteria, genetic techniques, and on standard techniques used in applications of microbiology (clinical, food, industrial, and aquatic). Lect. 2, Lab. 4. Prerequisites: BIO 103 or 105 and CHM 103.

 

MIC        260                                                                                                                                     Cr. 1–3

Topics in Microbiology

Varying topics in microbiology with a specific title assigned to each. Offered by resident faculty or visiting lecturers. Prerequisite: MIC 230. Repeatable for credit—maximum 6.

 

MIC        299                                                                                                                                     Cr. 1–2

Introduction to Microbiology Research

An opportunity to participate in laboratory or field research experience under the direction of a faculty member. Depending on the nature of the research project, study will involve participation in laboratory or theoretical work in addition to selected readings and instruction. A written report to the supervising faculty member is an expected outcome. Admission by instructor's consent and department approval. Completion of safety training required prior to beginning research. Repeatable for credit — maximum 4.

 

MIC        350                                                                                                                                     Cr. 3

Bacterial Diversity

A survey of the bacteria. Lectures will cover bacterial classification and the structure, physiology, ecology, and applications of various groups of bacteria. Special emphasis will be on the more unique species and those of industrial, ecological and environmental importance. The laboratory will involve enrichment and isolation procedures for selective groups of bacteria. Lect. 2, Lab. 3. Prerequisite: MIC 230.

 

MIC        406/506                                                                                                                             Cr. 4

Immunology

An introduction to how the immune system protects against infectious disease and how it

can contribute to disease. A discussion of fundamental characteristics of innate and acquired immunity is followed by study of antigens, antibodies, the major histocompatibility complex, T and B lymphocyte recognition of antigen and response, cytokines and immune regulation, hypersensitivity reactions including allergies,and the immune system in AIDS. Lect. 2, Lab. 4. Prerequisites: MIC 230; BIO 303 or 313 and

CHM 300 or 303 recommended.

 

MIC        407/507                                                                                                                             Cr. 4

Pathogenic Bacteriology

The study of pathogenic bacteria and their relationships to disease; principles of infection and pathogenesis, and unique properties of pathogens. Laboratory emphasis is on techniques for isolation and identification of pathogenic bacteria. Not applicable to biology major; may be applied to the microbiology, medical laboratory science major and/or degree as well as an elective for the biology biomedical concentration. Lect. 2, Lab 4. Prerequisites: MIC 230 and 406 (may be taken concurrently).

 

MIC        416/516                                                                                                                             Cr. 5

Microbial Genetics

An in-depth study of the bacterial and bacteriophage genome with emphasis on the central dogma. Specific topics include DNA replication, transcription and translation, DNA mutation and repair, regulation of gene expression, mechanisms of genetic exchange, plasmid structure and function, transposition, gene mapping and recombinant DNA technology. Laboratory emphasis is on the techniques used in bacterial mutagenesis, genetic exchange, gene mapping, and gene cloning. Lect. 2, Lab. 6. Prerequisites: MIC 406, four semesters of college chemistry including organic, and admitted to microbiology major. Offered Sem. I.

 

MIC        420/520                                                                                                                             Cr. 3

Introductory Virology

An introduction to viruses and their interactions with host organisms. Special emphasis is placed on the structure and replication cycles of virus families with medical importance. Prerequisites: MIC 230 and 416 or BIO 306 or 435, and three semesters of college chemistry to include organic chemistry. Offered Sem. II.

 

MIC        421/521                                                                                                                             Cr. 2

Virology Laboratory

A laboratory course designed to introduce fundamental techniques used to study viruses in medicine, biotechnology and research. Emphasis is on procedures used to safely handle viruses, grow them in tissue culture, and the molecular biological, biochemical and immunological techniques used to detect and analyze viruses. Lab. 4. Prerequisites: MIC 230 and 416 or BIO 306 or 435, and three semesters of college chemistry to include organic chemistry. Offered Sem. I.

 

 

 

 

MIC        425/525                                                                                                                             Cr. 5

Bacterial Physiology

An in-depth study of bacterial structure and function, catabolic and anabolic pathways, regulation, and macromolecular synthesis. Laboratory emphasis is on current techniques used to examine bacterial structure and metabolism such as macromolecular separations and quantification, use of radioisotopic tracers and quantification of enzyme activity. Lect. 2, Lab. 6. Prerequisites: MIC 406, MTH 150 or higher, CHM 301 and 300 (or 303), and admitted to microbiology major. Offered Sem. II.

 

MIC        426/526                                                                                                                             Cr. 4

Food Microbiology

A study of environmental factors affecting the growth, activity, and destruction of micro-

organisms in food; principles of food spoilage; preservation of foods, including basic methods and their application to foods; food-borne intoxications and infections; indicator organisms; sanitation and microbiological standards in foods. Laboratory instruction includes quality control methods, sampling methods, techniques to identify important microorganisms in foods, and data interpretation and analysis. Lect. 2, Lab. 4. Prerequisites: MIC 230; BIO 412 strongly recommended. Offered Sem. II.

 

MIC        427/527                                                                                                                             Cr. 3

Industrial and Fermentation Microbiology

A study of microbiology and biochemistry of food fermentations; bioconversions; production of antibiotics, vitamins, amino acids and organic acids. Starter culture systems will be examined.  Prerequisite: MIC 230; MIC 426 strongly

recommended. Offered Sem. I.

 

MIC        428/528                                                                                                                             Cr. 2

Fermentation Microbiology Laboratory

Principles of fermentation science and biotechnology with emphasis on industrial and food fermentation processes. Laboratory emphasis is on the use of various fermentation systems that generate useful products including fermented food and beverages, pharmaceuticals, fine chemicals and other gene products. Lab. 4. Prerequisites: 

MIC 426 or 427 and three semesters of college chemistry. Offered. Sem. II.

 

MIC        434/534                                                                                                                             Cr. 3

Aquatic Microbial Ecology

An ecological study of bacteria, cyanobacteria and algae of aquatic ecosystems. Topics include microbial strategies for survival under various environmental conditions, the role of micro-organisms in biogeochemical cycling of elements, interactions of microorganisms with other aquatic biota, the role of microorganisms in pollution problems, and applications of microbial ecology to biotechnology. Laboratory emphasis is on experimental design and sampling techniques, quantification of microbial biomass, and measurement of microbial activities in aquatic habitats. One weekend field trip required. Lect. 2, Lab. 3. Prerequisites: MIC 230 and three semesters of college chemistry; BIO 341 strongly recommended. Offered Sem. I, alternate years.

 

MIC        450                                                                                                                                     Cr. 1–3

Internship in Microbiology

An academically relevant field experience in government, industry, business or community agencies. Students must have their internships approved and be advised by the department. Students must be on their internship worksite during the semester for which they are registered for academic credit. Maximum of two credits applicable to major. Repeatable for credit — maximum 8. Pass/Fail grading.

 

MIC        454/554                                                                                                                             Cr. 2

Mechanisms of Microbial Pathogenicity

The study of mechanisms of microbial pathogenicity including both overt microbial factors and complex interactions with the host that produce symptoms of disease. The cellular, biochemical, molecular, and genetic bases for modern understanding of microbial disease will be included. Prerequisites: MIC 406 (or equivalent) and MIC 407 (or equivalent). Offered Sem. II.

 

MIC        460/560                                                                                                                             Cr. 1–3

Symposium in Microbiology

Varying topics in microbiology with a specific title assigned to each. Offered by resident faculty or visiting lecturers. Prerequisite: MIC 230. Repeatable for credit—maximum 6.

 

MIC        461                                                                                                                                     Cr. 1

Capstone in Microbiology

A seminar-style course designed for students to review and discuss basic concepts necessary for a career in the biological sciences and to assess their major in microbiology. This course will cover basic concepts of resume and cover letter writing, quantitative skills, computer literacy, and current topics in biology and microbiology. Students are expected to actively participate in an assessment of their major, and participate in discussions on major issues and developments in the biological sciences. Prerequisite: senior standing; recommended for seniors in their final semester. Pass/Fail grading.

 

MIC        479                                                                                                                                     Cr. 1–2

Microbiology Laboratory Assistant

An opportunity to assist in the preparation and instruction of a microbiology laboratory. Students will be expected to assist in preparation of course materials, demonstrate proper techniques, and evaluate student performance. Admission by instructor’s consent. Completion of safety training required. Lect. 2, Lab. 6. Repeatable for credit — maximum 4. Pass/Fail grading.

 

MIC        489                                                                                                                                     Cr. 1–2

Independent Study in Microbiology

A directed reading/project course covering a standard body of knowledge within the discipline but outside that offered through regularly scheduled courses. Under the direction of the supervising faculty member, study may involve a review of current literature. A written report or project is an expected outcome. Admission by instructor's and department approval. Completion of safety training required prior to beginning a laboratory or field-based project. Repeatable for credit — maximum 4.

 

MIC        499                                                                                                                                     Cr. 1–3

Independent Research in Microbiology

An opportunity to pursue individual research topics under the direction of a faculty member. Depending on the nature of the research project, study is expected to involve substantial laboratory or theoretical work in addition to literature review and instruction. Students are expected to develop research skills related to microbiology. In addition to a written report to the supervising faculty member, expected outcomes may include: laboratory notebooks, experimental devices, software, papers and presentations to departments and regional meetings. Admission by instructor’s consent and department approval. Completion of safety training required prior to beginning research. Repeatable for credit — maximum 8.