MIC 230 Fundamentals of Microbiology -002UW-La Crosse


Instructor: Bonnie Jo Bratina, 3029 Cowley Hall

Class meets at 8:50-9:45, T, H, 141 Carl WimberlyHall


||      Lecture Syllabus      ||      Unit 1 links     ||      Unit 1 Study Guide      ||      Unit 2 links       ||      Unit 2 Study guide    ||      Unit 3 links      ||      Final Study guide      ||

Lecture Syllabus

Text: Madigan, M.T., J.M. Martinko, J. Parker. 1997 Brock, Biology of Microorganisms, 11th ed.

Date          Topic                                                                                                             Reading

Sept.   4  Introduction, Scope and History of Microbiology                                         2-20, 300-308

            6  Early Earth, Prok../Euk. Groups, Taxonomy /Phylogeny                               22-27, 35-36, 309-328, 448-465

           11  Structure/Function of the Bacterial Cell:  Cell Envelope                                 63-72 (review. Ch 3)

           13  Structure/Function of the Bacterial Cell:  Cell Envelope                                74-81

           18  Structure/Function of the Bact. Cell: Motility, Cytoplasm, Inclusions           82-100

           20  Bacterial Cultivation/Growth, Nutrient classifications                                  28-29, 102-107, 136-150

           25  Bacterial Physiology:  Enzymes and Energetics *10-Pt Quiz*                    108-117

   27  Bacterial Physiology:  Fermentation                                                             117-120, 571-575

 Oct.        2  Bacterial Physiology:  Respiration                                                                 120-123, 127-128, 557-558

             4  Bacterial Physiology: Chemiosmosis and ATP Synthesis                             123-127, 545-549, 130-133

   9  75-Point Exam I 

 11  Prokaryotic Molecular Biology:  Structure and Function of DNA       167-170, 174-181, 188-203


 16  Bacterial Genetics:  Mutations and Mutants                                               257-265, 284-287

           18  Bacterial Genetics:  Recombination, Repair, and Use of Mutants                266-268      

           23  Bacterial Genetics:  Gene Transfer (conjugation)                                        274-279, 282

           25  Virology: Classification, Structure and Replication *15-Point Quiz*        231-242, 245-246, 253-254

           30  Bac. Gen.: Gene Transf.(transduction/transformation                               268-274   

  Nov.      1  Recombinant DNA Technology                                                                  287-288, 970-972, 981-991

             6  Control of Microorganisms:  Physical Effects                                             150-165, 670-677

             8  Control of Microorganisms: Chemical Effects                                            677-681, 924-930

           13  Chemotherapy                                                                                             681-685, 692-699

           15  Pathogenic Bacteriology:  Virulence Factors                                               12-14, 701-702, 710-721, 821-827

           20  75-Point Exam II

           22 Thanksgiving - no class

           27  Pathogenic Bacteriology:  Examples of Diseases Caused by Microbes      789-791, 848-858, 869-873, 890-

                                                                                                                                     895, 899-904, 914-920, 930-938

          29  Host Parasite Relationships; Immunology: Nonspecific Defense               703, 722-736

 Dec.     4  Immunology:  Specific Defense Mechanisms *10-Point Quiz*               736-739, 743-749, 751-754   

           6  Food and Industrial Microbiology                                                               942-968

          11  Environmental Microbiology and Microbial Ecology                                  614-631, 647-655, 907-914

  19   125-Point Final exam, 12:15-2:15 p.m. (part comprehensive)


Grading: Exam I  75     92-100% = A     Review Sessions: Quiz 1: Sept 24, 6:30-7:30pm
  Exam II 75     88-92%   = AB          Exam I:  Oct. 8, 6:30-7:30pm
  Final Exam   125     82-88%   = B          Exam II: Nov. 19, 6:30-7:30pm
  Quizzes/Assignments  50     78-82%   = BC       Final:  Dec. 18, 7:00-8:00pm
  Poster  25     70-78%   = C          
  Laboratory 270     60-69%  = D     All review sessions are in Rm. 301 CH
                         Total: 620                

Note:  Any student with a documented disability (e.g. physical, psychiatric, vision or hearing, etc.) who needs to arrange reasonable accommodations must contact the instructor and the Disability Resource Services Office (165 Murphy Library, 785-6900) at the beginning of the semester.  Students who are currently using the Disability Resource Services office will have a copy of a contract that verifies they are qualified students with disabilities who have documentation on file in the Disability Resource Services office.



Useful Unit 1 links

NOTE: All links to the Microbe Library (sponsored and run by the American Society of Microbiology) will first send you to an authorization page.  If all you are doing is viewing the site/animation then all you need to do is agree to the conditions in order to get to the link you want.

Binary fission



Catabolism and anabolism



Aerobic and Anaerobic respiration/ATP synthesis (interactive animation)



Aerobic respiration animation



Animation of electron transport and chemiosmosis in bacteria





1st Exam Study Guide


            The first exam will be 75 pts and will cover all the lectures up to (but not including) the Prokaryotic Molecular Biology lecture. The exam will consist of several styles of examination questions including matching, fill in the blank, diagrams and short answer essay.

Specific suggestions of material to understand include (but is not limited to):

»Life is driven by nothing else but electrons, by the energy given off by these electrons while cascading down from the high level to which they have been boosted up by photons.  An electron going around is a little current.  What drives life is thus a little electric current, kept up by the sunshine. All the complexities of intermediary metabolism are but lacework around this basic fact.» -Albert Szent-Györgyi



Useful Unit 2 links


Prokaryotic transcription



Prokaryotic translation





2nd Exam Study Guide


            The second exam will be 75 pts and will cover all the lectures through (and including) Chemical control and antibiotics.  The exam will consist of several styles of examination questions including matching, fill in the blank, and short answer essay.

Specific suggestions of material to understand include (but is not limited to):





Useful Unit 3 links

Case study on the Bubonic Plague



Understanding The Immune System

Developed by Lydia Schindler, Donna Kerrigan M.S., Jeanne Kelly

Illustrates the immune system, complex network of specialized cells and organs that distinguishes between self and foreign molecules inside the body. Explains that a malfunctioning immune system can cause allergies or arthritis and can fail to stop the growth of cancer cells. On National Cancer Institute site.



Phagocytosis and bacterial pathogens






Final Exam Study Guide


            The final exam will be 125 pts - approximately 60-65% will be from the third unit with the remaining 40-35% comprehensive.  As before, the exam will consist of several styles of examination questions including matching, fill in the blank, diagrams and short answer essay.  The comprehensive section will also contain some multiple choice questions.

Specific suggestions of material to understand include (but is not limited to):

For your selected disease (these will be handed out in class), write a paragraph briefly describing the disease, giving the full name of the causative agent, the mode of transmission, virulence factors involved, the host response(s) -if known- or other relevant factors.



"All organisms are nothing but a bag of other organisms walkin' around."
- Tom Miller, UC Riverside, on All Things Considered, NPR, June 28, 2004