Molecular Biology lecture consists of four sections: central dogma, regulation of gene expression, cellular processes, and current topics in molecular biology. Another focus of the course is in learning how to read primary literature.
In Molecular Biology Lab students work on two projects that are part of the research programs of other faculty in biochemistry or cell and molecular biology. This allows the students to participate in a real research experiment. This also exposes them to several aspects of biotechnology research; CRISPR, QPCR, site directed mutagenesis, cloning, and computer modeling. The students write their results in a peer-reviewed journal format.
Bioinformatics is a team taught course that focuses on the many applications of bioinformatics and the theoretical algorithms underlying these computer programs. There are four sections to the course; Databases, Phylogenetics, Genomics and Proteomics.
Molecular Basis of Disease and Drug Action examines the biological basis of many non-infectious and non-cancerous diseases and the drugs used to treat them. For each disease the students are given three perspectives; pathology, pharmacology and clinical. This course is team taught by Scott Cooper (pathology), Aaron Monte (pharmacology) and several M.D.s from local hospitals (clinical). There are five units in the course; Pathology and Pharmacology, Inflammation, Cardiovascular, Neurological, and Genetics. Students also give oral presentations on assigned diseases.
Radiation Biology is a course primarily for nuclear medical technology (NMT) and radiation therapy (RT) majors. It focuses on the effects of radiation on biological systems. The lab involves both exploring the properties of radiation, and the effects of radiation on biomolecules and cells.
My research focuses on the effects of hibernation on blood clotting. Ground squirrels that hibernate have increased blood clotting times to prevent clots from forming as their hearts slow and blood pressure drops. We are trying to understand how the squirrels regulate primary and secondary hemostasis to accomplish this. I typically have 6-8 teams of 3-4 students working on different aspects of this project. This research is funded by the NIH.
B.S. Biochemistry - Michigan State University, 1986
Ph.D. Biochemistry - University of Wisconsin-Madison, 1992
Post-Doc Pathology - University of North Carolina at Chapel Hill, 1993-1995