Sierra Colavito

Assistant Professor

Specialty area(s)

Breast Cancer Cell Biology

Current courses at UWL

BIO 306- Genetics
BIO 306L- Genetics Lab
BIO 105: General Biology

Teaching history

BIO 105: General Biology

BIO 306- Genetics

BIO 306L- Genetics Lab

BIO 435/535- Molecular Biology


Professional history

My research focuses on examining signal transduction pathways in breast cancer. Specifically, I am interested in understanding more about breast cancer stem cells, and trying to identify new strategies for targeting these cells.
Potential Graduate Students: Please e-mail me for more information

Research and publishing

Colavito S, Zou MR, Yan Q, Nguyen, DX, and Stern DF (2014). Significance of glioma-associated oncogene homolog 1 (GLI1) expression in claudin-low breast cancer and crosstalk with the NFkB pathway. Breast Cancer Res. 2014 Sep 25;16(5):444

Wilson KA*, Colavito S*, Schulz V, Wakefield PH, Sessa W, Tuck DP, and Stern DF. (2011) NFBD1/MDC1 Regulates Cav1 and Cav2 independently of DNA damage and p53. Molecular Cancer Research, 9, 766-781 (*co-first authors).

Colavito S, Prakash R, and Sung P. (2010) Promotion and Regulation of Homologous Recombination by DNA Helicases. Methods, 51, 329-35.

Colavito S, Macris-Kiss M, Seong C, Gleeson O, Greene E, Klein H, Krejci L, and Sung P. (2009) Functional Significance of the Rad51-Srs2 Complex in Rad51 Presynaptic Filament Disruption. Nucleic Acids Research, 37, 6754-6764.

Seong C, Colavito S, Kwon Y, Sung P, Krejci L. (2009) Regulation of Rad51 Recombinase Presynaptic Filament Assembly via Interactions with the Rad52 Mediator and the Srs2 Anti-recombinase. Journal of Biological Chemistry, 284, 24363-24371.

Pinnell J, Lindeman P, Colavito S, Lowe C, Savage RM. (2006). The Divergent Roles of the Segmentation Gene Hunchback. Integrative and Comparative Biology, 46, 519-532.

Au N, Kuester-Schoeck E, Mandava V, Bothwell LE, Canny SP, Chachu K, Colavito SA, Fuller SN, Groban ES, Hensley LA, O’Brien TC, Shah A, Tierney JK, Tomm LL, O’Gara TM, Goranov AI, Grossman AD, Lovett CM (2005). Genetic Composition of the Bacillus subtilis SOS System. Journal of Bacteriology, 187, 7655-7666.

Stegmaier K, Ross KN, Colavito SA, O’Malley S, Stockwell BR, Golub TR. (2004). Gene Expression-Based High-Throughput Screening (GE-HTS) and Application to Leukemia Differentiation. Nature Genetics, 36, 257-263.


Post-doctoral Fellow, Yale University and the American Cancer Society, 2010-2014

PhD, Yale University, Genetics, 2010

BA, Williams College, Biology 2002