Profile for Tisha King-Heiden

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Tisha King‑Heiden

University of Wisconsin-La Crosse

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Specialty area(s)

Reproductive physiology & toxicology and developmental toxicology

Brief biography

I use small fish models (zebrafish and fathead minnows) to study the effects of exposure to environmental contaminants during early life stages on development and health later in life (mostly reproduction).  


Teaching history

Bio 105 (General Biology)

Bio 260 (Special Topics: Environmental and Health Effects of Water Pollution)

Bio 312 (Human Anatomy & Physiology I)

Bio 313 (Human Anatomy & Physiology II)

Bio 421/521 (Comparative Vertebrate Endocrinology)

Bio 441/541 (Environmental Toxicology)

Bio 718 (Advanced Human Physiology I)

Research and publishing

RESEARCH PUBLICATIONS (*indicates undergraduate student; graduate student):

S Victoria, S Duffy*, E Harrahy and TC King-Heiden.  2022.  Embryonic exposure to thiamethoxam reduces survival and alters neurobehavior of fathead minnows.  Env. Tox. and Chem.  In press.

A Stenzel*, H Wirt*, A Patten*, B Theodore*, and TC King-Heiden.  2019.  Larval exposure to environmentally relevant concentrations of triclosan impairs metamorphosis and reproductive fitness in zebrafish.  Repro. Toxicol. 87:79-86.

R Ryan, C Belby, TC King-Heiden, RJ Haro, J Ogorek, and G Gerrish.  2019. The role of macroinvertebrate in the distribution of lead (Pb) within a marsh ecosystem. Hydrobiologica. 827:337-352.

H, Wirt*, R Botka*, KE Perez, and TC King-Heiden.  2018.  Embryonic exposure to environmentally relevant concentrations of triclosan impairs foraging efficiency in zebrafish larvae.  Env. Tox. and Chem.  37(12):3124-3133.

AJ Olson*, T Cyphers, G Gerrish, C Belby, and TC King-Heiden.  2018. Evaluating the toxicity of contaminated sediments from an urban wetland: A case study approach to develop a molecular biomarker for exposure to lead in zebrafish. J Toxicol Environ Health (A). 81(18):924-938.

Q Liu, RH Klingler, B Wimpee, M Dellinger, TC King-Heiden, J Wehr Grzybowski*, SL Gerstenberger, DN Weber, and MJ Carvan, III.  2016.  Maternal methylmercury from a wild-caught walleye diet induces developmental abnormalities in zebrafish. Repro. Toxicol. 65:272-282.

A Saley*, M Hess*, K Miller*, D Howard, and TC King-Heiden.  2016. Cardiac toxicity of triclosan in developing zebrafish.  Zebrafish: Special Issue on Toxicology.  13(5): 399-404.

N Carmosini, S Grandstrand*, and TC King-Heiden. 2016.  Developmental toxicity of triclosan in the presence of dissolved organic carbon: Moving beyond standard acute toxicity assays to understand ecotoxicological risk. Zebrafish: Special Issue on Toxicology.  13(5): 424-431.

Lor*, Y, A Revak*, J Weigand*, E Hicks*, D Howard, and TC King-Heiden.  2015.  Juvenile exposure to vinclozolin shifts sex ratios and impairs reproductive capacity of zebrafish. Repro Tox 58:111-118.

RJ Hutz, M Carvan, III, JK Larson, Q Liu, RV Stelzer, TC King-Heiden, MG Baldridge, N Shahnoor and K Julien.  2014. Familiar and novel reproductive endocrine disruptors: xenoestrogens, dioxins and nanoparticles. Current Trends Endocrinol. 7:111-122.

TR Baker, TC King-Heiden, W Heideman, RE Peterson. 2014. Dioxin induction of transgenerational inheritance of disease in zebrafish. Mol Cell Endocrinol. 398:36-41.  Invited Review.

Chollett*, D, KE Perez, and TC King-Heiden.  2014. Embryonic exposure to sublethal concentrations of 2,3,7,8-TCDD impairs prey capture by zebrafish larvae. Environ. Toxicol. Chem. 33(4): 784-790. Selected by editorial board as one of top 5 exceptional papers in ETC 2014.

Wiecinski, PN, KM Metz, TC King-Heiden, K Lewis, AN Mangham, RJ Hamers, W Heideman, RE Peterson, and JA Pederson. 2013. Toxicity of oxidatively degraded quantum dots. Environ. Sci. and Technol.  47(16):9132-9139.

King-Heiden, TC, V Mehta, KM Xiong, KA Lanham, DS Antkiewicz, A Ganser*, W Heideman, RE Peterson.  2012. Reproductive and developmental toxicity of dioxin in fish. Mol. Cell Endo. 354(1-2):121-38. 

King-Heiden, TC, PN Wiecinski, AN Mangham, KM Metz, D Nesbit, JA Pederson, RJ Hamers, W Heideman, and RE Peterson. 2009. Quantum Dot nanotoxicity assessments using the zebrafish embryo. Environ. Sci. and Technol. 43(5):1605-1611.

King-Heiden, TC, J Spitsbergen, W Heideman, and RE Peterson.  2009.  Persistent adverse effects on health and reproduction caused by exposure of zebrafish to 2,3,7,8-tetrachlorodibenzo-p-dioxin during early development and gonad differentiation. Tox Sci. 109(1):75-87.

Hill, AJ, TC King-Heiden, W Heideman, W, and RE Peterson.  2009.  Roles of ARNT2 in zebrafish embryonic development. Zebrafish. 6(1): 79-91.

King-Heiden, TC, CA Struble, ML Rise, MJ Hessner, RJ Hutz, and MJ Carvan, III. 2008. Molecular targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin within the zebrafish ovary: Insights into TCDD’s ovarian toxicity.  Reprod. Toxicol.  25(1):47-57.

King-Heiden, TC, E Dengler, WJ Gao, W Heideman, and RE Peterson.  2007.  Developmental toxicity of low generation PAMAM dendrimers in Zebrafish.  Toxicol. Appl. Pharm. 225:70-79.

Hutz, RJ, MJ Carvan III, MG Baldridge, LK Conely, and TC King-Heiden.  2006.  Environmental toxicants and effects on female reproductive function, Review. Trends in Repro. Biol. 2:1-11.

King-Heiden, TC, MJ Carvan, III, and RJ Hutz.  2006.  Inhibition of follicular development, vitellogenesis, and 17β estradiol concentrations in zebrafish following chronic, sublethal dietary exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.  Tox. Sci. 90(2): 490-499.

King-Heiden, TC, RJ Hutz, and MJ Carvan, III.  2005.  Accumulation and maternal transfer of TCDD: Effects on reproductive success of female zebrafish. Tox Sci.  87(2):497-507.

King-Heiden, TC, A Neal Haines, C Manire, J Lombardi, and TJ Koob.  2005.  Ultrastructure and permeability of the egg capsule of the bonnethead shark, Sphyrna tiburo. J. Exp. Zool. 303A(7):577-589.


KE Perez and TC King-Heiden. 2018. Geometric morphometrics as a tool to evaluate teratogenic effects in zebrafish (Danio rerio).  Teratogenicity Testing: Methods and Protocols.  In Methods in Molecular Biology.  Springer in press.

Carvan III, MJ, TC King-Heiden, and H Tomasiawicz.  2005.  The Utility of Zebrafish as a Model for Toxicological Research.  In Biochemistry and Molecular Biology of Fishes, vol 6 Environmental Toxicology.  TP Mommsen and TW Moon, eds.  Elsevier BV. Pp. 3-41.


TC King-Heiden and ME Litster. 2018. Using learning cycle based modules to promote a better understanding of the evolutionary processes that shape human health. J of Bio Ed, in press.

Gerrish, G, T King-Heiden, A, Sanderfoot, M Abler, K Perez.  2014.  Building the impetus for change: an across curriculum Vision & Change initiative in Biology.  J College Sci Teaching. 44(4):28-35.



Tisha King-Heiden, Biology, received the award for a Presidential Citation at SETAC SciCon4 on Nov. 18 in a virtual conference. This award was in recognition for her leadership in DEI efforts and as an Executive Committee Member for this international science society.

Submitted on: Nov. 19, 2021



Tisha King-Heiden, Biology, co-authored the article "The Importance of Diverse Mentors in the Sciences" in SETAC Globe published on Thursday, Jan. 14 by ET&C. This opinion piece was written with colleagues from SETAC North America in response to the recent Wall Street Journal op-ed condemning first lady elect, Jill Biden, for using her doctoral prefix and the now retracted Nature Communications article that used inappropriate analyses to suggest female mentorship has a negative impact on the careers of others in science. Our piece is intended to highlight the current data that actually supports the opposite findings, to identify data gaps that remain in this field, and to offer a call to action to increase diversity of mentors in the sciences.

Submitted on: Jan. 14, 2021



Tisha King-Heiden, Biology, was named the At-Large Executive Committee Member of the Society of Environmental Toxicology and Chemistry - North American on Nov. 20.

Submitted on: Nov. 24, 2020



Tisha King-Heiden, Biology, Biology, co-authored the article "A “Call In” to Be a Better Ally" in SETAC Globe published on Aug. 27 by ET&C. This opinion piece written with colleagues from the Inclusive Diversity Committee of the Society of Environmental Toxicology and Chemistry (SETAC) was in response to the on-going BLM movement towards racial justice, and to call folx in to use "ally as a verb" in our efforts to make STEM fields more inclusive.

Submitted on: Sept. 28, 2020



Tisha King-Heiden, Biology, was named (elected) to the Board of Directors for Society of Environmental Toxicology and Chemistry, North America.

Submitted on: Feb. 4, 2019


Memberships & affiliations

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