Biology kudos

Tisha King-Heiden, Biology

Tisha King-Heiden, Biology, Biology, co-authored the article "A “Call In” to Be a Better Ally" in SETAC Globe published on Aug. 27 by ET&C. This opinion piece written with colleagues from the Inclusive Diversity Committee of the Society of Environmental Toxicology and Chemistry (SETAC) was in response to the on-going BLM movement towards racial justice, and to call folx in to use "ally as a verb" in our efforts to make STEM fields more inclusive.

Submitted on: Sept. 28

Daniel Walgenbach, Alex Steil, Cade Armstrong, College of Science & Health, Jacob Kailing, College of Science & Health and Jennifer Klein, Biology

Daniel Walgenbach, Cade Armstrong, College of Science & Health and Jacob Kailing, College of Science & Health, all Biochemistry (ASBMB Cert) BS; Alex Steil, Biology (Cell and Molecular Concentration); and Jennifer Klein, Biology, Biology; co-authored the article "The calmodulin redox sensor controls myogenesis" in PLOS ONE published on Sept. 17 by Public Library of Science (PLOS). Muscle aging is accompanied by blunted muscle regeneration in response to injury and disuse. Oxidative stress likely underlies this diminished response, but muscle redox sensors that act in regeneration have not yet been characterized. Students in Molecular Biology Lab (Bio 436) contributed to using the CRISPR-Cas9 gene editing system to introduce a single amino acid substitution M109Q that mimics oxidation of methionine to methionine sulfoxide in one or both alleles of the CALM1 gene, one of three genes encoding the muscle regulatory protein calmodulin, in C2C12 mouse myoblasts. When signaled to undergo myogenesis, mutated myoblasts failed to differentiate into myotubes. Students in Advanced Microscopy (Bio 449/549) found that although early myogenic regulatory factors were present, cells with the CALM1 M109Q mutation in one or both alleles were unable to withdraw from the cell cycle and failed to express late myogenic factors. We have shown that a single oxidative modification to a redox-sensitive muscle regulatory protein can halt myogenesis, suggesting a molecular target for mitigating the impact of oxidative stress in age-related muscle degeneration. Research was funded by the National Institutes of Health (National Institute of Aging). Over 100 UWL students contributed to this publication! Thank you to all of those students who braved the waters of course-embedded research and found success.

Submitted on: Sept. 19

Barrett Klein

Barrett Klein, Biology, authored the article "Slumber in a cell: honeycomb used by honey bees for food, brood, heating… and sleeping" in PeerJ published on Aug. 5 by PeerJ. What do honey bees do when they are inside honeycomb cells? Spoiler: It includes sleeping.

Submitted on: Aug. 7

Veronica Yovovich, Christopher Wilmers and Meredith Thomsen

Veronica Yovovich, University of California-Berkeley; Christopher Wilmers, University of California-Santa Cruz; and Meredith Thomsen, Biology; co-authored the article "Pumas' fear of humans precipitates changes in plant architecture" in Ecosphere and was accepted for publication by John Wiley & Sons.

Submitted on: Aug. 3

Barrett Klein

Barrett Klein, Biology, authored the article "Exposing the murky depths: The value of scientific illustration for freshwater science - a multi-part series (part 1) " in "In the Drift" (newsletter) published on June 17 by Society for Freshwater Science . Ross Vander Vorste (UWL Biology), as editor, invited me to submit an article about the value of scientific illustration.

Submitted on: June 19

Forging a connection between science and art